Hello Lise,
Thank you for your post.
The Store Manager for PrestaShop is a desktop application that operated with the remote MySQL database.
Once you install the Store Manager, you have to configure a database connection.
You're welcome to use the Database Connection Wizard:
http://store-manager-for-prestashop-documentation.emagicone.com/quick-start-guide/connection-wizard
Let us know if you have any other questions.